The Missile and Space Intelligence Center (MSIC) is an intelligence organization that is part of the Defense Intelligence Agency of the United States. MSIC is located at Redstone Arsenal in Huntsville, Alabama. It is charged with producing scientific and technological intelligence on adversary surface-to-air missiles (SAMs), and ballistic missile systems with ranges less than 1000 km.

This intelligence includes characteristics, capabilities and limitations of foreign military systems, including data about related weapons, weapon system material, research, development, test, evaluation and production.